The book offers a clear and engaging account of how technical science and technological development in Czechia evolved from the post-Czechoslovak transition of 1993 to the mature, infrastructure-rich, and internationally integrated system of 2025. It traces the major stages of this transformation, from institutional reorganisation and post-socialist adaptation to European integration, strategic specialisation, digital modernisation, and the consolidation of advanced research infrastructures. The book shows how Czechia built a distinctive technological model grounded in strong technical universities, public research organisations, industrial R&D, and close links between science and production. Particular attention is given to the leading branches of contemporary Czech technological development, including electron microscopy and scientific instrumentation, high-performance computing, artificial intelligence and robotics, cybersecurity and network technologies, automotive engineering and Industry 4.0, transport engineering, and other high-technology sectors. The edition also highlights the contribution of leading Czech researchers, engineers, and innovators whose work shaped the modern profile of these fields. Written in a concise but analytically rich style, the book combines historical overview, institutional analysis, technological mapping, and the study of key scientific and engineering achievements. It is especially valuable for interns, students, researchers, policy specialists, and professionals seeking a reliable introduction to the scientific and technological development of contemporary Czechia. Readers will find here not only a history of national technical progress, but also a model of how a medium-sized European state can build technological competitiveness through engineering depth, research infrastructure, and strategic integration into international scientific networks. This volume forms part of the wider series Implementation of Innovations: Experience of the Czech Republic, presenting Czech achievements across key branches of science and industry.